Synthesis and Biological Activity of Aminophosphabetaines with Long-chain Substitutes at the Nitrogen Atom

Aminophosphabetaines containing higher alkyl substituents at the nitrogen atom were synthesized by a three-stage procedure. The structure of the products was proved by IR and NMR spectroscopy, mass spectrometry, and X-ray diffraction analysis. All the synthesized compounds showed moderate antimicrob...

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Bibliographic Details
Published inRussian journal of organic chemistry Vol. 58; no. 8; pp. 1093 - 1098
Main Authors Davletshin, R. R., Gayneev, A. M., Davletshina, N. V., Galkina, I. V., Ivshin, K. A., Shulaeva, M. P.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.08.2022
Springer Nature
Springer Nature B.V
Subjects
Antiinfectives and antibacterials
Biological activity
Chemistry
Chemistry and Materials Science
Chemistry, Organic
Infrared spectroscopy
Mass spectrometry
Nitrogen
NMR spectroscopy
Organic Chemistry
Physical Sciences
Science & Technology
Synthesis
synthesis
aminophosphabetaine
biological activity
X-ray diffraction analysis
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Summary:Aminophosphabetaines containing higher alkyl substituents at the nitrogen atom were synthesized by a three-stage procedure. The structure of the products was proved by IR and NMR spectroscopy, mass spectrometry, and X-ray diffraction analysis. All the synthesized compounds showed moderate antimicrobial activity against B. cereus and S. aureus bacterial strains, as well as Candida albicans fungi.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428022080048