Expression and Correlation Research of MicroRNA10a-5p and PIK3CA in Middle Ear Cholesteatoma

• Published in: Journal of International Advanced Otology Vol. 19; no. 3; pp. 212 - 216
• Main Authors: Yang, Jing, Yan, Wei, Tang, Susu, Huang, Zhikun, Ye, Mingyuan, Lu, Zheng, Liu, Qianxu
• Format: Journal Article
• Language: English
• Published: Turkey AVES 01.06.2023
• Subjects: Cell Proliferation - genetics; Cholesteatoma, Middle Ear - genetics; Class I Phosphatidylinositol 3-Kinases - genetics; Class I Phosphatidylinositol 3-Kinases - metabolism; Humans; MicroRNAs - genetics

BACKGROUND: This study aimed to examine the roles of miR-10a-5p and phosphatidylinositol-4,5-bisphosphonate 3-kinase catalytic subunit α in the pathogenesis of middle ear cholesteatoma. METHODS: We enrolled 27 patients with middle ear cholesteatoma and collected samples of intraoperative cholesteato...