Antibiotic Resistance Among Salmonella spp. Isolated from Feces of Patients with Acute Diarrhea in Gwangju Area, Korea, during 2000-2009

• Published in: The Korean Journal of Microbiology Vol. 49; no. 2
• Main Authors: Kim, T.S., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Kim, M.J., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Kim, S.H., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Seo, J.J., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Kee, H.Y., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Chung, J.K., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Kim, E.S., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Moon, Y.W., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Ha, D.R., Public Health and Environment Institute of Gwangju, Gwangju, Republic of Korea, Kim, M.K., Namseoul University, Cheonan, Republic of Korea, Lim, S.K., Animal and Plant Quarantine Agency, Gyeonggi-do, Republic of Korea, Nam, H.M., Animal and Plant Quarantine Agency, Gyeonggi-do, Republic of Korea
• Format: Journal Article
• Language: English
• Published: 01.06.2013
• Subjects: antibiotic resistance; GASTROENTERITE; GASTROENTERITIS; SALMONELLA
• ISSN: 0440-2413
• DOI: 10.7845/kjm.2013.3032

Antibiotic susceptibility was examined for 596 Salmonella isolates from patients with acute gastroenteritis during 2000-2009 in Gwangju area in South Korea. Of 16 antibiotics tested, ampicillin resistance (43%) was the most commonly observed resistance among the 596 Salmonella sp. isolates, followed by tetracycline (35.9%), nalidixic acid (31.5%), and chloramphenicol (26.2%). Antibiotic resistance varied among serotypes: The highest resistance of S. Enteritidis and S. Typhimurium was to ampicillin (51.1%) and tetracycline (77.9%), respectively. A total of 89 resistance patterns were observed, and 26% (155/596) of Salmonella isolates were susceptible to all antibiotics tested in this study. About 21% (127/596) and 15% (87/596) of the isolates were resistant to one and two antibiotics, respectively. The rest of Salmonella isolates (227/596, 38%) were resistant to three or more antibiotic agents. The highest multi-drug resistance (MDR) was observed in serotype S. Paratyphi B (76.5%), followed by S. Typhimurium (58.2%), and S. Enteritidis (40.2%). The most common resistance pattern of MDR isolates was ampicillinchloramphenicol- nalidixic acid-ticarcillin (36/227, 15.8%), most of which (35/36, 97.2%) were S. Enteritidis.