Epigenetics of human parathyroid tumors

• Published in: International journal of endocrine oncology Vol. 4; no. 2; pp. 103 - 111
• Main Authors: Chiara, Verdelli, Sabrina, Corbetta
• Format: Journal Article
• Language: English
• Published: London Future Medicine Ltd 01.05.2017
• Subjects: Cancer; Deoxyribonucleic acid; DNA; DNA methylation; Enzymes; Epigenetics; Gene expression; Genomes; histone; histone methyltransferases; Investigations; MicroRNAs; miRNAs; Mutation; Neuroendocrine tumors; parathyroid tumors; primary hyperparathyroidism; Tumors

Parathyroid tumors are common endocrine neoplasia associated with primary hyperparathyroidism, a metabolic disorder sustained by parathormone hypersecretion. The epigenetic scenario in parathyroid tumors is beginning to be decoded. Here, main findings are reviewed: hypermethylation of specific DNA C...