Efficient synthesis of benzo[g]- and benzo[h]chromene derivatives by one-pot three-component condensation of aromatic aldehydes with active methylene compounds and naphthols

A convenient procedure is reported for the synthesis of benzo[g]- and benzo[h]chromene derivatives via one-pot three-component condensation of aromatic aldehydes with malononitrile or ethyl cyanoacetate and 1- or 2-naphthol in the presence of 10 mol % of titanium tetrachloride as catalyst. The react...

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Bibliographic Details
Published inRussian journal of organic chemistry Vol. 42; no. 12; pp. 1813 - 1815
Main Authors Kumar, B. Sunil, Srinivasulu, N., Udupi, R. H., Rajitha, B., Reddy, Y. Thirupathi, Reddy, P. Narsimha, Kumar, P. S.
Format Journal Article
LanguageEnglish
Published NEW YORK Springer Nature 01.12.2006
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
HETEROCYCLIC SYNTHESIS
NITRILES
INTERMOLECULAR HYDROAMINATION REACTIONS
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Summary:A convenient procedure is reported for the synthesis of benzo[g]- and benzo[h]chromene derivatives via one-pot three-component condensation of aromatic aldehydes with malononitrile or ethyl cyanoacetate and 1- or 2-naphthol in the presence of 10 mol % of titanium tetrachloride as catalyst. The reactions require no solvent; they are characterized by simple experimental procedure and easy isolation and can be performed on enlarged scale.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428006120098