Bioequivalence of the Highest Dose Strength Fixed-Dose Combination Tablet Of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects

Background In type 2 diabetes mellitus, the combined use of agents with complementary mechanisms of action improves glucose control via correction of multiple pathophysiologic defects. Fixed-dose combination (FDC) therapy can offer not only these benefits, but also potentially increase patient compl...

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Bibliographic Details
Published inClinical therapeutics Vol. 39; no. 8; p. e53
Main Authors Cho, Y.-S., Lee, S. Hyang, Jung, J. Hyuk, Lim, H.-S., Bae, K.-S.
Format Journal Article
LanguageEnglish
Published Bridgewater Elsevier Inc 01.08.2017
Elsevier Limited
Subjects
Antidiabetics
Controlled release
Diabetes mellitus
Generic drugs
Internal Medicine
Medical Education
Metformin
Tablets
Online AccessGet full text
ISSN0149-2918
1879-114X
DOI10.1016/j.clinthera.2017.05.165

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Summary:Background In type 2 diabetes mellitus, the combined use of agents with complementary mechanisms of action improves glucose control via correction of multiple pathophysiologic defects. Fixed-dose combination (FDC) therapy can offer not only these benefits, but also potentially increase patient compliance.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2017.05.165