Asymptomatic Solitary Mastocytoma with Negative Darier’s Sign

Mastocytosis is a heterogenous group of disorders characterised by clonal proliferation of mast cells accumulating in single or multiple organs in children or adults. Skin is the most common organ involved in children. It usually presents as a nodule or plaque, yellow to tan-brown in colour remainin...

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Bibliographic Details
Published inJournal of clinical and diagnostic research Vol. 14; no. 5; pp. WD01 - WD03
Main Authors Fathima, Azra, Muralidhar, Krishnakanth, Veeraraghavan, Mahalakshmi, Madhu, R, Joseph, Leena Dennis, Sundaram, Murugan
Format Journal Article
LanguageEnglish
Published JCDR Research and Publications Private Limited 01.05.2020
Subjects
good prognosis
noduloplaque
non-itchy
paediatric mastocytosis
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Summary:Mastocytosis is a heterogenous group of disorders characterised by clonal proliferation of mast cells accumulating in single or multiple organs in children or adults. Skin is the most common organ involved in children. It usually presents as a nodule or plaque, yellow to tan-brown in colour remaining asymptomatic or may become red and itchy on rubbing indicating Darier’s sign positivity which helps in clinical diagnosis of mastocytosis. This case is of a three-month-old baby who presented with solitary asymptomatic noduloplaque with negative Darier’s sign which was clinically suspected to be mastocytosis and was confirmed by histopathology and immunohistochemistry.
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2020/43794.13689