Assessment of bronchial responsiveness on exposure to isometric exercise during different phases of menstrual cycle: A pilot study

Objectives: The present study was planned to assess the effects of gonadal steroids (estrogen and progesterone) on bronchial responsiveness, before and after handgrip exercise, during different phases of menstrual cycle. Materials and Methods:In this study, 30 healthy (25-40 years), non-athletic, ad...

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Published inIndian journal of medical sciences Vol. 67; no. 1; p. 38
Main Authors Bhandari, Bharti, Bedi, M, Varshney, V
Format Journal Article
LanguageEnglish
Published Mumbai Medknow Publications and Media Pvt. Ltd 01.01.2013
Medip Academy
Subjects
Airway (Medicine)
Asthma
Birth control
Bronchi
Hormones
Hormones, Sex
Isometric exercise
Measurement
Menstrual cycle
Menstruation
Methods
Physiological aspects
Womens health
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Summary:Objectives: The present study was planned to assess the effects of gonadal steroids (estrogen and progesterone) on bronchial responsiveness, before and after handgrip exercise, during different phases of menstrual cycle. Materials and Methods:In this study, 30 healthy (25-40 years), non-athletic, adult female volunteers were studied. The various pulmonary function parameters (FVC, FEV 1 , PEFR, FEF 25-75% ) were recorded with a spirometer under resting conditions and then within five minutes of cessation of isometric exercise. Recordings were taken during the Menstrual phase (MP), Proliferative phase (PP), and Luteal phase (LP) of menstrual cycle and were confirmed by plasma levels of estrogen and progesterone. The oral temperature was recorded during each phase of the menstrual cycle. Results : Under resting conditions, the above-mentioned parameters did not reveal significant differences during the three phases. A significant fall was observed only in the Peak Expiratory Flow Rate (PEFR) during all the phases after handgrip, but there was a non-significant decline in the other parameters. Conclusion : By this study we conclude that the physiological changes in hormone levels during the menstrual cycle are not in themselves associated with changes in airway responsiveness before and after the handgrip test. The general fall seen in the pulmonary parameters could be due to fatigue or psychic factors.
ISSN:0019-5359
1998-3654
DOI:10.4103/0019-5359.120696