Effect of a low-protein diet on chemiluminescence production by leukocytes from uremic patients

Chemiluminescence (CL) emission from leukocytes was studied in 20 uremic patients after ingestion of opsonized zymosan. CL production was impaired when compared with control groups. Six months after a low-protein, low-phosphorus diet supplemented with essential amino acids and ketoanalogues (SD) was...

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Bibliographic Details
Published inNephron (2015) Vol. 48; no. 4; p. 315
Main Authors Aparicio, M, Vincendeau, P, Gin, H, Potaux, L, Bouchet, J L, Martin-Dupont, P, Morel, D, de Precigout, V, Bezian, J H
Format Journal Article
LanguageEnglish
Published Switzerland 1988
Subjects
Adult
Aged
Dietary Proteins - administration & dosage
Female
Humans
Leukocytes - metabolism
Leukocytes - physiology
Luminescent Measurements
Male
Middle Aged
Phagocytosis
Phosphorus - administration & dosage
Urea - blood
Uremia - blood
Uremia - diet therapy
Uremia - immunology
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Summary:Chemiluminescence (CL) emission from leukocytes was studied in 20 uremic patients after ingestion of opsonized zymosan. CL production was impaired when compared with control groups. Six months after a low-protein, low-phosphorus diet supplemented with essential amino acids and ketoanalogues (SD) was started, a significant improvement in CL production was observed. SD may be expected to decrease the susceptibility of uremic patients to bacterial infections.
ISSN:1660-8151
2235-3186
DOI:10.1159/000184950