Neurologic disorders of mineral metabolism and parathyroid disease

Disorders of mineral metabolism may cause neurologic manifestations of the central and peripheral nervous systems. This is because plasma calcium stabilizes excitable membranes in the nerve and muscle tissue, magnesium is predominantly intracellular and is required for activation of many intracellul...

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Bibliographic Details
Published inHandbook of Clinical Neurology Vol. 120; pp. 737 - 748
Main Authors Agrawal, Lily, Habib, Zeina, Emanuele, Nicholas V.
Format Book Chapter Journal Article
LanguageEnglish
Published Netherlands Elsevier Health Sciences 2014
Subjects
Humans
Hypercalcemia
hypocalcemia
Metabolic Diseases - complications
Minerals - metabolism
muscular
Nervous System Diseases - etiology
neurologic
parathyroid
Parathyroid Diseases - complications
Parathyroid Diseases - diagnosis
Parathyroid Diseases - etiology
vitamin D
Hypercalcemia
muscular
parathyroid
hypocalcemia
neurologic
vitamin D
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Summary:Disorders of mineral metabolism may cause neurologic manifestations of the central and peripheral nervous systems. This is because plasma calcium stabilizes excitable membranes in the nerve and muscle tissue, magnesium is predominantly intracellular and is required for activation of many intracellular enzymes, and extracellular magnesium affects synaptic transmission. This chapter reviews abnormalities in electrolytes and minerals which can be associated with several neuromuscular symptoms including neuromuscular irritability, mental status changes, cardiac and smooth muscle changes, etc.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISBN:0702040878
9780702040870
ISSN:0072-9752
DOI:10.1016/B978-0-7020-4087-0.00049-8