Acute myocarditis and myocardial infarction induced by Paraphenylenediamine poisoning. Interest of angiocoronarography

• Published in: International journal of cardiology Vol. 113; no. 3; pp. E93 - E95
• Main Authors: Brahmi, Nozha, Kouraichi, Nadia, Blel, Youssef, Mourali, Sami, Thabet, Hafedh, Mechmeche, Rachid, Amamou, Mouldi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ireland Ltd 18.11.2006
• Subjects: Acute Disease; Adult; Angiocoronarography; Coronary Angiography; Female; Humans; Male; Myocardial infarction; Myocardial Infarction - chemically induced; Myocardial Infarction - diagnostic imaging; Myocarditis; Myocarditis - chemically induced; Myocarditis - diagnostic imaging; Paraphenylenediamine; Phenylenediamines - poisoning; Poisoning; Suicide, Attempted; Myocarditis; Myocardial infarction; Poisoning; Angiocoronarography; Paraphenylenediamine
• ISSN: 0167-5273; 1874-1754
• DOI: 10.1016/j.ijcard.2006.05.034

We present 2 cases of myocardial damage induced by Paraphenylenediamine (PPD) poisoning in young patients without any history of cardiovascular disease. ECG findings revealed the presence of localized ST segment elevation in precordial leads (V1–V4) in the first case and (V3–V6) in the second associated to an increase of the serum troponine T level at 23 ng/ml (case 1) and 29.7 ng/ml (case 2). The transthoracic echocardiography was in favour of diffuse myocarditis in the first case and of localized myocarditis or septo-apical myocardial infarction in the second. The angiocoronarography performed for the first time in the second case conclude on a septo-apical hypokinesia of the left ventricular resulting of a coronary spasm of the anterior interventricular artery.