Syringocystadenoma papilliferum located at the nipple: Description of an extremely rare case with review of the literature

Syringocystadenoma papilliferum (SCAP) is a rare, benign tumor of the apocrine sweat glands, and only two nipple-located SCAP cases have been reported. Very few cases of malignant transformation and metastasis have been reported. We share our experience with SCAP located at the nipple that recurred...

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Bibliographic Details
Published inTurkish Journal of Surgery Vol. 35; no. 2; pp. 151 - 154
Main Authors Peker, Yasar Subutay, Urkan, Murat, Hamcan, Salih, Cicek, Ali Fuat, Gulcelik, Mehmet Ali
Format Journal Article
LanguageEnglish
Published Ankara AVES 01.06.2019
Turkish Surgical Association
Subjects
Basal cell carcinoma
Cancer metastasis
Carcinoma
Genitalia
Hyperplasia
Nevus
Skin cancer
Tumors
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Summary:Syringocystadenoma papilliferum (SCAP) is a rare, benign tumor of the apocrine sweat glands, and only two nipple-located SCAP cases have been reported. Very few cases of malignant transformation and metastasis have been reported. We share our experience with SCAP located at the nipple that recurred with intraductal papilloma (IP). A female patient aged 26 years presented to our clinic with a mass at the posterior of the left nipple. The mass was excised, and the pathology report revealed SCAP. The patient had no recurrence for 1 year, but the mass recurred later in the same location. Re-excision was planned and conducted. Diagnosis of the second excised mass according to the pathology report was forid-type ductal epithelial hyperplasia and IP. SCAP may be located in female genitals, extremities, and trunk but these are rarer than in the head and neck. This is the third case reporting SCAP at the nipple. SCAP may be related to nevus sebaceous, resulting in basal cell carcinoma or syrigocystadenocarcinoma papilliferum; however, no data have been reported about the relation of SCAP with I P. The relation may be due to microscopic characteristics of SCAP, including the presence of papillary processes between two epithelial alignments. As a conclusion of this case presentation, SCAP of the nipple must be followed up for IP transformation or recurrence. Further evaluation may be needed for this dark side of the rare and little-known pathological entity; however, because of its rareness, it seems troublesome to diagnose. Keywords: Intraductal papilloma, syrigocystadenocarcinoma papilliferum, syringocystadenoma papilliferum
ISSN:2564-6850
2564-7032
DOI:10.5578/turkjsurg.4176