New-Onset and Persistent Insulin-Dependent Diabetes in Patients With COVID-19: A Peruvian Experience

Type 2 diabetes mellitus (T2DM) has been recognized as a risk factor for severe coronavirus disease 2019 (COVID-19) infection, and COVID-19 in diabetic patients is associated with a poor prognosis. New evidence suggests that patients with T2DM may experience diabetic ketoacidosis (DKA) or hyperglyce...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 14; no. 7
Main Authors Ramos-Yataco, Anthony, Salcedo Davila, Emanuel A, Meza, Kelly, Harbuz-Miller, Inga
Format Journal Article
LanguageEnglish
Published Palo Alto Cureus Inc 26.07.2022
Cureus
Subjects
Case reports
Coronaviruses
COVID-19
Diabetes
Diabetic ketoacidosis
Endocrinology/Diabetes/Metabolism
Hyperglycemia
Infectious Disease
Insulin
Insulin resistance
Viral infections
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Summary:Type 2 diabetes mellitus (T2DM) has been recognized as a risk factor for severe coronavirus disease 2019 (COVID-19) infection, and COVID-19 in diabetic patients is associated with a poor prognosis. New evidence suggests that patients with T2DM may experience diabetic ketoacidosis (DKA) or hyperglycemic hyperosmolar state (HHS) if infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is limited literature on new-onset diabetes in patients infected by SARS-CoV-2 without a history of diabetes. We present a case series of three patients who developed new-onset diabetes while suffering from acute COVID-19 infection; they presented with DKA even though they had no prior history or risk factors for diabetes. They remain persistently insulin-dependent several months post-recovery.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.27272