Epidemiological, clinical, biological and evolutionary profile of scorpion envenomed children under one year to 15 years in the Souss Massa region of Morocco

• Published in: Toxicon (Oxford) Vol. 247; p. 107832
• Main Authors: Darkaoui, Bouchra, El Hidan, Moulay Abdelmounaim, Lafnoune, Ayoub, Arourd, Driss, Belli, Hassan, Cadi, Rachida, Filali, Ouafaa Aniq, Oukkache, Naoual
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 28.08.2024
• Subjects: Biological and clinical parameters for Morocco; Mortality; Physiopathology; Scorpionism; Stings; Biological and clinical parameters for Morocco; Stings; Scorpionism; Mortality; Physiopathology
• ISSN: 0041-0101; 1879-3150; 1879-3150
• DOI: 10.1016/j.toxicon.2024.107832

Morocco is one of the main countries affected in North African with the scorpion envenomations. Faced with the threat, significant morbidity and a major risk of death especially in children, a detailed identification of scorpionic profile of stings remains important for health authorities at national or even regional level. The current study aims to establish the epidemiological, clinical, biological and evolutionary data of the scorpionism by analyzing 383 cases of scorpion stings in children from three age groups (<1 year, 1–5 years and >5 years), admitted at the Regional Hospital Hassan II-Agadir in the Souss Massa region during the period of 9 years and 10 months from January 2013 to October 2022. Our results showed that patients under 1 year of age presented the most severe cases and had the highest mortality rate. However, the clinical signs and symptoms observed illustrated severe damages to vital systems, particularly the cardiovascular, neurological and pulmonary systems, although the signs associated with the latter were present only in cases admitted in grades 2 and 3 for the three age categories studied. Fluctuations in vital constants (temperature and peripheral oxygen saturation, blood pressure, heart rate and respiratory rate), biochemical parameters (ASAT, ALAT, urea and blood creatine, as well as blood sugar) and CBC results revealed major functional disturbances in vital organs, especially in envenomated cases admitted in grade 3. A positive correlation was mentioned between the state of evolution and the various epidemiological parameters, digestive symptoms, as well as signs and symptoms linked to hemodynamic state, general and neurological state. The main interest is to illustrate the seriousness of scorpion envenomations, especially in the high-risk population, for whom an improved therapeutic approach in health centers will undoubtedly be reinforced, and the admission of immunotherapy, as a fundamental part of the treatment, remains important. [Display omitted] •The first research in scorpion envenomed children with three age categories in Souss Massa region, central Morocco.•The pulmonary symptoms appear only in patients admitted in grades 2 and 3.•The scorpion envenomations disrupt vital constants and biological parameters.•The patients less than 1 year old who are admitted in grade 3 represent the high rate of death.