The consistent use of recombinant and plasma coagulation factors in the intensive care of massive obstetric hemorrhage

• Published in: Vestnik anesteziologii i reanimatologii Vol. 17; no. 3; pp. 101 - 108
• Main Authors: Kuligin, A. V., Lushnikov, A. V., Zeulina, E. E.
• Format: Journal Article
• Language: English; Russian
• Published: New Terra Publishing House 28.06.2020
• Subjects: coagulopathy; massive obstetric hemorrhage; recombinant and plasma factors of the blood coagulation system
• ISSN: 2078-5658; 2541-8653
• DOI: 10.21292/2078-5658-2020-17-3-101-108

Massive obstetric hemorrhage is one of the most threatening complications of pregnancy, delivery and early postpartum period, which are part of the triad of leading causes of maternal mortality both in the world and in the Russian Federation. In recent years, to stop coagulopathy, which is one of the clinical manifestations of massive obstetric hemorrhage, recombinant and plasma factors of the blood coagulation system are successfully used, which include a concentrate of prothrombin complex and activated coagulation factor VII (eptacog alfa activated). The authors present results of successful consistent use of the blood coagulation system factors within comprehensive intensive care of coagulopathy in a patient with massive obstetric hemorrhage.