Δ8(14)-steroids in the bacterium Methylococcus capsulatus

The 4,4-dimethyl and 4α-methyl sterols of the bacterium Methylococcus capsulatus were identified as 4,4-dimethyl- and 4α-methyl-5α-cholest-8(14)-en-3β-ol and 4,4-dimethyl- and 4α-methyl-5α-cholesta-8(14),24-dien-3β-ol. Sterol biosynthesis is blocked at the level of 4α-methyl Δ8(14)-sterols.

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Bibliographic Details
Published in	Biochemical journal Vol. 159; no. 2; pp. 267 - 271
Main Authors	Bouvier, P, Rohmer, M, Benveniste, P, Ourisson, G
Format	Journal Article
Language	English
Published	01.11.1976
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Summary:	The 4,4-dimethyl and 4α-methyl sterols of the bacterium Methylococcus capsulatus were identified as 4,4-dimethyl- and 4α-methyl-5α-cholest-8(14)-en-3β-ol and 4,4-dimethyl- and 4α-methyl-5α-cholesta-8(14),24-dien-3β-ol. Sterol biosynthesis is blocked at the level of 4α-methyl Δ8(14)-sterols.
ISSN:	0264-6021
DOI:	10.1042/bj1590267