Complete remission of disseminated Langerhans cell sarcoma after stem cell transplantation A case report

Summary With fewer than 100 cases described in the English literature so far, Langerhans cell sarcoma represents an orphan malignant disease deriving from histiocytic cells. Clinical course is extremely aggressive and associated with poor survival rates, especially in disseminated condition. Herein,...

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Bibliographic Details
Published inMemo - Magazine of European medical oncology Vol. 13; no. 1; pp. 102 - 105
Main Authors Schlintl, Verena, Schlick, Konstantin, Russ, Gudrun, Gampenrieder, Simon Peter, Monzo Fuentes, Claudia, Kos, Tea, Renneberg, Felix, Rettenbacher, Lukas, Gradl, Johann, Sotlar, Karl, Hoffmann, Alexander, Greil, Richard
Format Journal Article
LanguageEnglish
Published Vienna Springer Vienna 01.03.2020
Subjects
Case Report
Medicine
Medicine & Public Health
Oncology
Chemotherapy
Autologous stem cell transplantation
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Summary:Summary With fewer than 100 cases described in the English literature so far, Langerhans cell sarcoma represents an orphan malignant disease deriving from histiocytic cells. Clinical course is extremely aggressive and associated with poor survival rates, especially in disseminated condition. Herein, we describe the case of a young patient with fulminant development of metastatic Langerhans cell sarcoma, who achieved persistent remission after polychemotherapy and subsequent high-dose chemotherapy with autologous stem cell transplantation.
ISSN:1865-5041
1865-5076
DOI:10.1007/s12254-019-00560-5