VRAM Versus ALT Flap Reconstruction for Large Head and Neck Defects: Does Weight Influence Complication Rate?

• Published in: Journal of personalized medicine Vol. 14; no. 7; p. 720
• Main Authors: Shires, Courtney B, Jackson, Jataiveus, Moskovitz, Jessica, Dewan, Karuna
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 03.07.2024
• Subjects: Abdominal surgery; Body weight; Cancer therapies; Head & neck cancer; Head and neck carcinoma; Hospitals; Obesity; Ostomy; Overweight; Patients; Radiation; Reconstructive surgery; Risk factors; Site location; Skin; Squamous cell carcinoma; Surgeons; Surgical outcomes; Underweight; VRAM; body weight; free flap; vertical rectus abdominus muscle; ALT; anterolateral thigh; obese
• ISSN: 2075-4426; 2075-4426
• DOI: 10.3390/jpm14070720

Obesity remains a high-level risk factor for various cancers. Yet, some research has shown that higher BMIs may improve survival outcomes, particularly for head and neck squamous cell carcinoma (HNSCC). While this is a clear deviation from the norm, it raises the question of what other effects obesity may have on head and neck cancer patients, including surgical outcomes. Choosing the most appropriate flap for patients can be difficult for even experienced surgeons. Head and neck reconstructive surgeries are no exception to this rule and can be especially challenging. To produce the most favorable outcomes, a physician must be able to combine all flap attributes including donor and recipient site location, flap thickness, as well as each patient's individual risk factors such as prior radiation. The purpose of this study was to compare the outcomes of vertical rectus femoris myocutaneous (VRAM) and anterolateral thigh (ALT) flaps in overweight and obese individuals with varying head and neck cancers leaving large-sized defects to the outcomes in normal and underweight patients. A retrospective chart review was conducted of VRAM and ALT flaps performed over a period of 12 months at our university hospital for large head and neck reconstruction. Of the 17 ALT patients, 80% (4/5) of the underweight patients, 57% (4/7) of the normal weight patients, 50% (1/2) of the overweight patients, and 33% (1/3) of the obese patients experienced complications. Of the 15 VRAM patients, 40% (2/5) of the underweight patients, 83% (5/6) of the overweight patients, and 50% (1/2) of the obese patients experienced complications. In our small sample size, a smaller percentage of obese patients with head and neck cancer who underwent flap reconstruction surgery had complications when undergoing ALT flaps than VRAM flaps, which contrasts with the normal and underweight patients, who had less complications with VRAM flaps than ALT flaps.