Magnesium-reinforced Electrospun Synthetic-polymer Nanofibers Designed for Promoting Tissue Growth

The creation of 3D nanofibers offering desirable functions for bone regeneration is developed due to the latest improvisations to the electrospinning technique. Synthetic polymers are among the best choices for medical usage due to their lower costs, high tensile properties, and ease of spinnability...

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Published inJournal of bionics engineering Vol. 21; no. 3; pp. 1412 - 1426
Main Authors Rafiq, Muheeb, Rather, Anjum Hamid, Khan, Rumysa Saleem, Wani, Taha Umair, Khan, Haseeb A., Alhomida, Abdullah S., Sheikh, Faheem A.
Format Journal Article
LanguageEnglish
Published Singapore Springer Nature Singapore 01.05.2024
Subjects
Artificial Intelligence
Biochemical Engineering
Bioinformatics
Biomaterials
Biomedical Engineering and Bioengineering
Biomedical Engineering/Biotechnology
Engineering
Review Article
Magnesium
Nanofibers
Bone regeneration
Tissue engineering
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Summary:The creation of 3D nanofibers offering desirable functions for bone regeneration is developed due to the latest improvisations to the electrospinning technique. Synthetic polymers are among the best choices for medical usage due to their lower costs, high tensile properties, and ease of spinnability compared to natural polymers. In this communication, we report a series of interventions to polymers modified with Mg-based fillers for ideal tissue engineering applications. The literature survey indicated that these filler materials (e.g., nano-sized particles) enhanced biocompatibility, antibacterial activity, tensile strength, and anti-corrosive properties. This review discusses electrospinning parameters, properties, and applications of the poly(ε-caprolactone), poly(lactic acid), poly(3-hydroxybutyric acid-co-3-hydroxy valeric acid), polyurethane, and poly(vinyl pyrrolidone) nanofibers when modified with Mg-based fillers. This report encourages researchers to use synthetic polymers with Mg as fillers and validate them for tissue engineering applications.
ISSN:1672-6529
2543-2141
DOI:10.1007/s42235-024-00495-6