Change in Chromatographic Parameters of Some Phenylpropanoids in Different Mobile Phases Under Reversed-Phase HPLC Conditions

The effect of the eluent composition (type and concentration of the organic and acid components) on the retention times and selectivity of the separation of some standard samples of phenylpropanoids under reversed- phase HPLC conditions is studied. Ethanol, being a nontoxic solvent, exhibited good c...

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Bibliographic Details
Published inPharmaceutical chemistry journal Vol. 58; no. 1; pp. 138 - 141
Main Authors Abramov, O. K., Ryabukha, A. F., Pletneva, I. V.
Format Journal Article
LanguageEnglish
Published New York Springer US 2024
Subjects
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
qualitative and quantitative analysis of plant raw materials and phytopreparations
HPLC
phenylpropanoids
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Summary:The effect of the eluent composition (type and concentration of the organic and acid components) on the retention times and selectivity of the separation of some standard samples of phenylpropanoids under reversed- phase HPLC conditions is studied. Ethanol, being a nontoxic solvent, exhibited good characteristics as an eluent for the separation of this group of substances. A mobile phase containing ethanol and organic acids could be recommended as an extractant for studies of plant raw material containing phenylpropanoids.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-024-03128-8