Treatment and Course of Community-Acquired Pneumonia Caused by Atypical Pathogens

To study the course of disease and outcomes in a group of patients with community-acquired pneumonia caused by atypical pathogens ( Mycoplasma pneumoniae, Legionella species, Coxiella burnetii, and Chlamydophila pneumoniae) according to the empiric treatment received. Of a total of 390 patients admi...

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Published inArchivos de bronconeumología (English ed.) Vol. 42; no. 9; pp. 430 - 433
Main Authors Álvarez, Ramón Fernández, Toste, Isabel Suárez, Cuadrado, Gemma Rubinos, Gonzálvez, Agustín Medina, Gullón Blanco, José Antonio, Martín, Isidro González
Format Journal Article
LanguageEnglish
Spanish
Published Spain 01.09.2006
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Summary:To study the course of disease and outcomes in a group of patients with community-acquired pneumonia caused by atypical pathogens ( Mycoplasma pneumoniae, Legionella species, Coxiella burnetii, and Chlamydophila pneumoniae) according to the empiric treatment received. Of a total of 390 patients admitted to our hospital with pneumonia between January 1996 and February 2001, the causative microorganism was an atypical pathogen in 89 cases. Patients were divided retrospectively into 2 groups according to the empiric treatment they received: group A, who had received an antibiotic regimen (quinolones or macrolides) that provided coverage for atypical pathogens; and group B, who had received treatment that did not provide such coverage. Clinical course was assessed in terms of the differences between the 2 groups in length of hospital stay, radiographic resolution, readmission at 30 days after discharge, and mortality. A total of 89 patients with pneumonia caused by atypical pathogens (39 in group A and 50 in group B) were studied. No significant between-group differences in the variables were found. In this group of patients hospitalized for community-acquired pneumonia, antibiotic regimens providing coverage for atypical pathogens did not improve either clinical or radiographic evolution. Estudiar la evolución de un grupo de neumonías extrahospitalarias causadas por gérmenes atípicos ( Mycoplasma pneumoniae, Legionella spp., Coxiella burnetii y Chlamydophila pneumoniae) en función del tratamiento empírico recibido. Entre enero de 1996 y febrero de 2001 ingresaron en nuestra unidad 390 casos de neumonía, de los que 89 estaban causados por gérmenes atípicos. Los pacientes se dividieron retrospectivamente en 2 grupos según el tratamiento empírico pautado: grupo A, al que se había proporcionado cobertura frente a gérmenes atípicos (quinolonas o macrólidos), y grupo B, al que no se había proporcionado dicha cobertura. Se estudió la evolución según las diferencias entre ambos grupos en la estancia hospitalaria, la resolución radiológica, el reingreso en el primer mes tras el alta y la mortalidad. El grupo de estudio lo constituyeron 89 pacientes con neumonía causada por gérmenes atípicos (39 en el grupo A y 50 en el B). Las variables estudiadas no mostraron diferencias significativas entre ambos grupos. En nuestra serie de neumonías extrahospitalarias la cobertura antibiótica frente a gérmenes atípicos no mejoró la evolución clínica y radiológica de los pacientes.
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ISSN:1579-2129
0300-2896
1579-2129
DOI:10.1016/S1579-2129(06)60564-8