Transplacental transmission of Venezuelan equine encephalitis virus in horses

Transplacental passage of Venezuelan equine encephalitis virus, epizootic strain P-676, occurred in four of nine fetuses studied. The mares were infected near term. Virus was recovered in high titer from fetal blood and organs, while no virus was detected in maternal blood but neutralizing antibodie...

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Bibliographic Details
Published inThe American journal of tropical medicine and hygiene Vol. 29; no. 4; p. 653
Main Authors Justines, G, Sucre, H, Alvarez, O
Format Journal Article
LanguageEnglish
Published United States 01.07.1980
Subjects
Animals
Antibodies, Viral - analysis
Encephalomyelitis, Equine - veterinary
Encephalomyelitis, Venezuelan Equine - immunology
Encephalomyelitis, Venezuelan Equine - transmission
Encephalomyelitis, Venezuelan Equine - veterinary
Female
Horse Diseases - immunology
Horse Diseases - transmission
Horses
Maternal-Fetal Exchange
Pregnancy
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Summary:Transplacental passage of Venezuelan equine encephalitis virus, epizootic strain P-676, occurred in four of nine fetuses studied. The mares were infected near term. Virus was recovered in high titer from fetal blood and organs, while no virus was detected in maternal blood but neutralizing antibodies were present. No evidence of in utero infection was found in two fetuses from mares infected with MF-8, another epizootic strain of Venezuelan equine encephalitis virus.
ISSN:0002-9637
1476-1645
DOI:10.4269/ajtmh.1980.29.653