Effect of the method of fabrication of polyvinyl alcohol films on the properties of immobilized trypsin

In order to develop a film wound dressing with proteolytic activity based on polyvinyl alcohol, the effect of the conditions of the preparation of the molding solution on the properties of trypsin immobilized in the film structure was studied. The dependence of the relative activity and enzyme stabi...

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Bibliographic Details
Published inTheoretical foundations of chemical engineering Vol. 45; no. 4; pp. 478 - 481
Main Authors Antipova, A. A., Yudanova, T. N., Malinkina, T. B., Karelina, I. M.
Format Journal Article
LanguageEnglish
Published Dordrecht SP MAIK Nauka/Interperiodica 01.08.2011
Subjects
Chemistry
Chemistry and Materials Science
Composite Technology
Industrial Chemistry/Chemical Engineering
Organic Polymer
polyethylene glycol
trypsin
wound dressing
bioactive polyvinyl alcohol film
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Summary:In order to develop a film wound dressing with proteolytic activity based on polyvinyl alcohol, the effect of the conditions of the preparation of the molding solution on the properties of trypsin immobilized in the film structure was studied. The dependence of the relative activity and enzyme stability on the order of the introduction of the components into the molding solution and the molecular weight of the polyethylene glycol additives was established.
ISSN:0040-5795
1608-3431
DOI:10.1134/S0040579510051021