Who Benefits from Nodal Field Irradiation?

Randomized clinical trials and meta-analyses have clearly demonstrated that radiation after definitive surgery can improve local-regional control and consequently breast cancer survival. There has been some controversy, however, regarding when and in which patient populations more extensive radiatio...

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Bibliographic Details
Published inCurrent breast cancer reports Vol. 3; no. 2; pp. 124 - 130
Main Author White, Julia
Format Journal Article
LanguageEnglish
Published New York Current Science Inc 01.06.2011
Subjects
Internal Medicine
Medicine
Medicine & Public Health
Oncology
Surgical Oncology
Breast cancer
Extended nodal irradiation
Postmastectomy radiation
Nodal irradiation after breast conservation
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Summary:Randomized clinical trials and meta-analyses have clearly demonstrated that radiation after definitive surgery can improve local-regional control and consequently breast cancer survival. There has been some controversy, however, regarding when and in which patient populations more extensive radiation to the nodal regions is warranted. This review focuses on the current evidence supporting the use of radiation and the rationale for determining patients who will derive the most benefit.
ISSN:1943-4588
1943-4596
DOI:10.1007/s12609-011-0046-4