The role of vascular capacitance in the genesis of essential hypertension

1. Analysis of relationships between blood volume, vascular capacitance, cardiopulmonary and peripheral blood volumes, labelled albumin disappearance rate, plasma renin activity, blood pressure and age was performed in essential hypertensive males. 2. The results indicate that capacitance bed constr...

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Bibliographic Details
Published inClinical science and molecular medicine. Supplement Vol. 3; p. 203s
Main Author Ulrych, M
Format Journal Article
LanguageEnglish
Published England 01.01.1976
Subjects
Age Factors
Blood Pressure
Blood Volume
Humans
Hypertension - etiology
Hypertension - physiopathology
Serum Albumin - metabolism
Vasomotor System - physiopathology
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Summary:1. Analysis of relationships between blood volume, vascular capacitance, cardiopulmonary and peripheral blood volumes, labelled albumin disappearance rate, plasma renin activity, blood pressure and age was performed in essential hypertensive males. 2. The results indicate that capacitance bed constriction probably occurs with age in essential hypertension leading to an increase in the product blood volume xvascular capacitance tone even in the presence of low blood volume. 3. A metabolic defect in the venous vascular bed along with an abnormality of regulation of renal sodium excretion is postulated.
ISSN:0144-4107
DOI:10.1042/cs051203s