Assessment Of Antibody Levels In A Population Vaccinated With Sputnik V

• Published in: Russian open medical journal Vol. 12; no. 1
• Main Authors: Gonzalez, Diego, Fortuna, Federico, Fritzler, Analy F., Jamardo, Juan J., Duarte, Eliana, Ibar, Carolina, Jacobsen, Dario G., Estevez, Maria E., Aguirre, J, Garzón, Belky B., Absi, Ruben, Repetto, Esteban M., Sanchez, Gelos Diego, Zopatti, Damian, Fabre, Bibiana
• Format: Journal Article
• Language: English
• Published: 01.03.2023
• ISSN: 2304-3415; 2304-3415
• DOI: 10.15275/rusomj.2023.0102

Objectives — The objective of our study was to assess humoral response in a population of health workers after vaccination with the first and second doses of Sputnik V. Methods — SARS-CoV-2 total antibodies (IgG and IgM) were measured, using the Centaur XPT autoanalyzer, Siemens®, in 530 serum samples taken from health workers in Buenos Aires vaccinated with Sputnik V. Results — After 21 days of the first dose application, 10 individuals (1.9%) presented antibody levels <1.0 (non-reactive), while 520 subjects (98.1%) responded with antibody values >1.0 (reactive). The results, obtained 21 days after the second dose, show that only 2 individuals (0.38%) had antibody levels <1.0 (non-reactive) and 528 (99.6%) responded with antibody values >1.0 (reactive). Conclusion — This study results implied that two doses of Sputnik V vaccine generated a proper antibody response in virtually the entire studied population.