Gastrointestinal manifestations of HIV infection

• Published in: Current gastroenterology reports Vol. 2; no. 4; pp. 283 - 293
• Main Authors: Wallace, M R, Brann, O S
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 01.08.2000
• Subjects: Abdominal Pain - etiology; Acidosis, Lactic - chemically induced; AIDS-Related Opportunistic Infections - complications; Antiretroviral Therapy, Highly Active; Biliary Tract Diseases - virology; Comorbidity; Cytomegalovirus Infections - complications; Esophageal Diseases - virology; Esophagitis - virology; Gastrointestinal Diseases - virology; Gastrointestinal Hemorrhage - virology; Hepatitis B - epidemiology; Hepatitis C - epidemiology; HIV Enteropathy - microbiology; HIV Infections - complications; HIV Infections - epidemiology; Humans; Liver Diseases - virology; Pancreatic Diseases - epidemiology; Pancreatic Diseases - virology; Protozoan Infections - complications; Rectal Diseases - virology; Reverse Transcriptase Inhibitors - adverse effects
• ISSN: 1522-8037; 1534-312X
• DOI: 10.1007/s11894-000-0020-1

Since the beginning of the AIDS pandemic, gastrointestinal (GI) problems have been among the most common features of the disease. Despite the introduction of highly active antiretroviral therapy (HAART) in 1995 and 1996, most HIV-infected patients continue to have GI complications. The clinician must be able to diagnose and treat the opportunistic gastrointestinal infections and neoplasms that occur in the advanced AIDS patient, as well as the treatment-induced symptoms and non-HIV-related GI disorders that predominate in early HIV disease. This review addresses the GI manifestations of HIV, with particular emphasis on new developments in the era of highly effective therapy.