Transforming growth factor‐β, interleukin‐17, and IL‐23 gene expression profiles associated with human peri‐implantitis

• Published in: Clinical oral implants research Vol. 28; no. 7; pp. e10 - e15
• Main Authors: Mardegan, Gustavo Pereira, Shibli, Jamil Awad, Roth, Leandro Amadeu, Faveri, Marcelo, Giro, Gabriela, Bastos, Marta Ferreira
• Format: Journal Article
• Language: English
• Published: Denmark 01.07.2017
• Subjects: Biopsy; Case-Control Studies; cytokines; Dentistry; Female; Gene Expression; Humans; IL‐17; IL‐23; Interleukin-17 - genetics; Interleukin-23 - genetics; Male; Middle Aged; Peri-Implantitis - genetics; peri‐implant bone loss; peri‐implantitis/peri‐implant diseases; Real-Time Polymerase Chain Reaction; RNA, Messenger - genetics; RT‐PCR; TGF‐β; Th1; Th2; Transforming Growth Factor beta - genetics; peri-implant bone loss; RT-PCR; IL-17; TGF-β; cytokines; IL-23; Th1; gene expression; peri-implantitis/peri-implant diseases; Th2

Objectives The mRNA expression profiles of IL‐23/Th17 and the Treg‐associated cytokine TGF‐β in peri‐implantitis are currently under research. This study characterized the IL‐17, IL‐23, and TGF‐β gene expression levels in healthy and diseased peri‐implant tissues and correlated these data with radio...