A CASE OF MALIGNANT ADENOMYOEPITHELIOMA OF THE BREAST

• Published in: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 61; no. 11; pp. 2900 - 2905
• Main Authors: YATSUGI, Hiroyuki, MASTUMOTO, Atsushi, ARAKI, Yasumi, KAIBARA, Atsushi, YASUNAGA, Masafumi, HAYASHI, Katsumi, YAMAUCHI, Kenji, ISOMOTO, Hiroharu, AOYAGI, Shigeaki
• Format: Journal Article
• Language: English
• Published: Japan Surgical Association 2000
• ISSN: 1345-2843; 1882-5133
• DOI: 10.3919/jjsa.61.2900

A61-year-old woman was seen at the hospital because she noticed a left breast mass. A well movable tumor was palpable in the C area of left breast. Ultrasonography revealed a 12×9×8mm demarcated iow-echoic region with slightly heterogeneous inside. Mammography visualized a partially irregular image in the left berast. Needle aspiration biopsy cytology disclosed nucleoli as well as relatively numerous cells, indicating class III. Under local anesthesia, an excisional biopsy was perfor-med. Aa a result of histopathological exploration, ductal carcinoma was diagnosed and a radical operation was performed. Despite the pathological diagnosis of ductal carcinoma, the tumor cells were positive for S-100 protein and HHF-35 and vascular infiltrating was revealed. The definite diagnosis of malignant adenomyoepithelioma was made. In the diagnosis of the disease, histopathological and electron microscopic findings are helpful. Adenomyoepithelioma manifesting malgnant features is so rare that only two cases have been reported in Japan.