Laparoscopic bilateral salpingo-oophorectomy for recurrent ovarian endometriotic cysts in a woman taking adjuvant tamoxifen for breast cancer: A case report

• Published in: Case reports in women's health Vol. 43; p. e00637
• Main Authors: Takeuchi, Hajime, Yagi, Koki, Tokunaga, Naho, Abe, Naoki, Matsuno, Mariko, Kira, Sachino, Hayashi, Sotaro, Lee, Lifa, To, Yoko, Nishiyama, Satoshi, Goto, Maki, Tsujioka, Hiroshi
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.10.2024; Elsevier
• Subjects: Endometriosis; Laparoscopic surgery; Long-term estradiol; Ovarian endometrioma; Tamoxifen; Uninterrupted menstruation; TAM; Uninterrupted menstruation; LEP; Ovarian endometrioma; Endometriosis; Laparoscopic surgery; Tamoxifen; Long-term estradiol; DNG
• ISSN: 2214-9112; 2214-9112
• DOI: 10.1016/j.crwh.2024.e00637

The case report describes the management of endometriotic cysts in a woman taking adjuvant tamoxifen. A diagnosis of endometriosis was made at the age of 38, and the condition was initially managed with a low-dose estrogen-progestogen combination; the patient then switched to dienogest at the age of 45. Following a diagnosis of breast cancer at the age of 46, dienogest was stopped and adjuvant tamoxifen treatment started. After 4 months the patient was diagnosed with bilateral ovarian cysts and underwent laparoscopic bilateral salpingo-oophorectomy. Endometriosis was diagnosed in both ovaries on histopathological examination. This case report describes progression of endometriosis in a tamoxifen user. •Tamoxifen administered for breast cancer exacerbates endometriosis.•Managing endometriosis while taking tamoxifen requires careful individual treatment.•Awareness required for recurrence of endometriosis with tamoxifen for breast cancer.•Regular gynecological examination is essential during Tamoxifen treatment.•Switch from Tamoxifen to aromatase inhibitors is advised post-surgery.