18F-FDG-PET findings of rare case of nonsecretory plasmablastic myeloma

• Published in: Annals of nuclear medicine Vol. 23; no. 9; pp. 807 - 811
• Main Authors: Kaibara, Hiroko, Kaida, Hayato, Ishibashi, Masatoshi, Kurata, Seiji, Otsubo, Korenori, Fujimoto, Kiminori, Uchida, Masafumi, Abe, Toshi, Kobayashi, Maiko, Doi, Ryousuke, Kunou, Yukiko, Okamura, Takashi, Oshima, Koichi, Hayabuchi, Naofumi
• Format: Journal Article
• Language: English
• Published: Japan Springer Japan 01.11.2009; Springer Nature B.V
• Subjects: Case Report; Female; Fluorodeoxyglucose F18 - metabolism; Humans; Imaging; Medicine; Medicine & Public Health; Middle Aged; Neoplasms, Plasma Cell - diagnostic imaging; Neoplasms, Plasma Cell - metabolism; Neoplasms, Plasma Cell - pathology; Nuclear Medicine; Positron-Emission Tomography; Radiography; Radiology; Rare Diseases - diagnostic imaging; Rare Diseases - metabolism; Rare Diseases - pathology; Nonsecretory myeloma; Plasmablastic type; Fluorine-18 fluorodeoxyglucose-positron emission tomography
• ISSN: 0914-7187; 1864-6433
• DOI: 10.1007/s12149-009-0300-2

A 61-year-old woman presented with pancytopenia and underwent a bone marrow biopsy. The patient was diagnosed with nonsecretory myeloma (plasmablastic type) based on both the bone marrow biopsy findings and her laboratory data. Fluorine-18 fluorodeoxyglucose-positron emission tomography ( 18 F-FDG-PET) was performed prior to chemotherapy showing diffuse bone marrow uptake, splenic uptake, and focal uptake of the right anterior chest wall. The patient underwent an 18 F-FDG-PET examination to evaluate the curative effects after three cycles of chemotherapy, and no abnormal uptake on 18 F-FDG-PET was found. Bone marrow biopsy to evaluate the curative effect showed no viable tumor cells. We present a rare case of nonsecretory plasmablastic myeloma detected by 18 F-FDG-PET.