Immunoglobulin A Vasculitis in a Patient on Hemodialysis and With a Metastatic Liver Lesion

We present the case of a 79-year-old man on hemodialysis with immunoglobulin A (IgA) vasculitis. He developed palpable purpura three weeks after having pneumonia. A skin biopsy showed leukocytoclastic vasculitis with IgA and C3 deposition. He received a topical corticosteroid for his IgA vasculitis....

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Published inCurēus (Palo Alto, CA) Vol. 13; no. 3; p. e13863
Main Authors Yamamoto, Naoki, Dejima, Akihiro, Hasatani, Kenkou
Format Journal Article
LanguageEnglish
Published United States Cureus 13.03.2021
Subjects
Allergy/Immunology
Dermatology
Nephrology
metastatic liver lesion
iga vasculitis
haemodialysis (hd)
henoch-schönlein purpura
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Summary:We present the case of a 79-year-old man on hemodialysis with immunoglobulin A (IgA) vasculitis. He developed palpable purpura three weeks after having pneumonia. A skin biopsy showed leukocytoclastic vasculitis with IgA and C3 deposition. He received a topical corticosteroid for his IgA vasculitis. He was also diagnosed with a metastatic liver lesion, which was thought to be of colorectal origin because of the elevations in carcinoembryonic antigen and cancer antigen 19-9 levels. The skin biopsy played an important role in the diagnosis of the patient on hemodialysis. Pneumonia and a metastatic liver lesion thought to be from colorectal cancer might be related to the pathogenesis of IgA vasculitis.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.13863