Field Performance and Public Health Response Using the BinaxNOWTM Rapid Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigen Detection Assay During Community-Based Testing

Abstract Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOWTM and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold....

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Published inClinical infectious diseases Vol. 73; no. 9; pp. e3098 - e3101
Main Authors Pilarowski, Genay, Marquez, Carina, Rubio, Luis, Peng, James, Martinez, Jackie, Black, Douglas, Chamie, Gabriel, Jones, Diane, Jacobo, Jon, Tulier-Laiwa, Valerie, Rojas, Susana, Rojas, Susy, Cox, Chesa, Nakamura, Robert, Petersen, Maya, DeRisi, Joseph, Havlir, Diane V
Format Journal Article
LanguageEnglish
Published US Oxford University Press 02.11.2021
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community-based SARS-CoV-2 testing
asymptomatic SARS-CoV-2 infection
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Summary:Abstract Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOWTM and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold. The specificity was 99.9%. Performance was high across ages and those with and without symptoms. Rapid resulting permitted immediate public health action.
Bibliography:ObjectType-Article-1
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ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciaa1890