A case of focal oral mucinosis of the hard palate

We report a case of 77-year-old woman with focal oral mucinosis (FOM) arising in the hard palate. The patient had noticed a nodular mass 8 years earlier and over this period she felt that it had gradually grown. The mass was 20mm in diameter, painless, and had a smooth surface. Magnetic resonance im...

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Bibliographic Details
Published inJapanese Journal of Oral and Maxillofacial Surgery Vol. 53; no. 6; pp. 378 - 381
Main Authors OKAMOTO, Noriko, TATEMOTO, Yukihiro, HAMAKAWA, Hiroyuki, YAMAMOTO, Tetsuya
Format Journal Article
LanguageEnglish
Published Japanese Society of Oral and Maxillofacial Surgeons 2007
Subjects
fibroblast
focal oral mucinosis
mucin
palatal neoplasm
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.53.378

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Summary:We report a case of 77-year-old woman with focal oral mucinosis (FOM) arising in the hard palate. The patient had noticed a nodular mass 8 years earlier and over this period she felt that it had gradually grown. The mass was 20mm in diameter, painless, and had a smooth surface. Magnetic resonance imaging of the lesion revealed high signal intensity on T2-weighted images. Because biopsy suggested a benign non-epithelial tumor, the tumor was resected under general anesthesia. Histological examination showed that the lesion consisted of well-localized myxomatous connective tissue. The tissue was stained with alcian blue, which disappeared after hyaluronidase digestion, indicating an abundance of acidic mucopolysaccharides. The fibroblast-like cells with mucin retention were immunohistochemically negative for S-100 protein. Finally, a review of diagnoses of FOM is presented.
ISSN:0021-5163
2186-1579
DOI:10.5794/jjoms.53.378