Five Years of Clinical Evaluation of Nonresorbable Membranes in the Treatment of Intrabony Defects Following Guided Tissue Regeneration

• Published in: Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) Vol. 38; no. 2; pp. 211 - 219
• Main Authors: Yoshinari, Nobuo, Tohya, Tosyo, Inagaki, Koji, Mori, Atsushi, Nishiyama, Saeko, Koide, Masanori, Suzuki, Hiroki, Ishikawa, Kazuhiro, Nagira, Tamaki, Amano, Katsuhiko, Noguchi, Toshihide
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY OF PERIODONTOLOGY 1996
• Subjects: Expanded polytetrafluoroethylene (ePTFE) membrane; Five years postsurgery; Flap debridement; Guided tissue regeneration; Nonresorbable membrane
• ISSN: 0385-0110; 1880-408X
• DOI: 10.2329/perio.38.211

The aim of the present study was to evaluate whether new attachment, gained following guided tissue regeneration (GTR) therapy, can be maintained over 5 years of maintenance therapy. Fourteen sites in 14 patients (average age 40.9 years, 21-57 years of age, 3 males and 11 females) with adult periodontitis were treated with the GTR technique (GTR group) and 14 sites in 14 patients average age 39.6 years, 23-54 years of (age, 5 males and 9 females) with adult periodontitis were treated with flap debridement (FOP group). Lesions in the GTR group included 1 site with a single wall defect, 11 sites with 2 intrabony wall defects and 2 sites with 3 intrabony wall defects. Lesions in the FOP group included 2 sites with a single wall defect, 9 sites with 2 intrabony wall defects and 3 sites with 3 intrabony wall defects. The sites which had undergone both procedures demonstrated improved gingival conditions including probing pocket depth (PD), clinical attachment level (CAL) and marginal tissue recession (MR) at 5 years after surgery. In the GTR and FOP groups, there were decreases in PD of 3.9±1.6mm and 2.9±1.5mm, gains in CAL of 3.2±1.8mm and 1.1±1.4mm and increases in MR of 0.7±1.3mm and 1.8±1.5mm, respectively. A significant attachment gain was obtained in the GTR group and this gain was significantly longer than that in the FOP group. During the 4 years of maintenance between the 1 and 5 year examinations, PD and CAL in both groups remained stable. These results demonstrate that CAL, obtained as the result of GTR therapy, can be maintained for periods of up to 5 years.