1,8-Naphthalimide-based fluorescent sensor with high selectivity and sensitivity for Zn2+ and its imaging in living cells

A novel 4-amino-1,8-naphthalimide-based fluorescent sensor with iminodiacetic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 34-fold enhancement in...

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Published inInorganic chemistry communications Vol. 101; pp. 117 - 120
Main Authors Liu, Daying, Deng, Xinxin, Yin, Xin, Wang, Yuting, Guo, Jing, Chen, Jiatong, Yang, Guangming, He, Huarui
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.03.2019
Subjects
Fluorescent sensor
Iminodiacetic acid
Naphthalimide
Zinc
Fluorescent sensor
Naphthalimide
Iminodiacetic acid
Zinc
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Summary:A novel 4-amino-1,8-naphthalimide-based fluorescent sensor with iminodiacetic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 34-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1,8-naphthalimide with a green color centered at 550 nm. [Display omitted] •A new 1,8-naphthalimide-based fluorescent Zn2+ sensor was synthesized.•High selectivity and sensitivity for sensing Zn2+•It was applied successfully to image Zn2+ in living cells.
ISSN:1387-7003
1879-0259
DOI:10.1016/j.inoche.2019.01.023