FIELD CANCERIZATION- AN APPRAISAL OF CONCEPTS AND RESEARCH

BACKGROUNDA large area of the genetically altered area around the tumour proper that appears clinically normal is called field cancerization. This field subsequently influences the prognosis as it can root to second field tumours i.e. recurrence or second primary tumours. Field cancerization has bee...

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Bibliographic Details
Published inJournal of evolution of medical and dental sciences Vol. 7; no. 53; pp. 5639 - 5642
Main Authors Anuradha, Ananthaneni, Ramani, Pratibha, Srinivas, Guduru Vijay, Babu, Undavalli Suresh, Kiresur, Mohammed Asif
Format Journal Article
LanguageEnglish
Published Akshantala Enterprises Private Limited 31.12.2018
Subjects
Cancer
Cancer recurrence
Carcinogenesis
Care and treatment
Esophageal cancer
Excision (Surgery)
Mouth cancer
Second primary cancer
Skin
Tumors
Youth smoking
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Summary:BACKGROUNDA large area of the genetically altered area around the tumour proper that appears clinically normal is called field cancerization. This field subsequently influences the prognosis as it can root to second field tumours i.e. recurrence or second primary tumours. Field cancerization has been described in the oral cavity, oropharynx, larynx; lung, vulva, oesophagus, cervix, breast, skin, colon and bladder. Studies have shown a comparatively higher frequency of local recurrences and second primary tumours after surgical resection in betel chewers than non-chewers probably due to the existence of field cancerization.KEY WORDSField, Micrometastasis, Second Primaries.
ISSN:2278-4748
2278-4802
DOI:10.14260/jemds/2018/1247