FIBROUS DYSPLASIA OF PROXIMAL PHALANX OF HAND A RADIOLOGICAL DIAGNOSIS AND HISTOPATHOLOGICAL CONFIRMATION

• Published in: Journal of evolution of medical and dental sciences Vol. 3; no. 21; pp. 5882 - 5885
• Main Authors: Khanduri, Shobha, Khanduri, Sachin, Parashari, Umesh C, Chhabra, Saakshi, Bhadury, Samarjit
• Format: Journal Article
• Language: English
• Published: Akshantala Enterprises Private Limited 26.05.2014
• Subjects: Diagnosis; Dysplasia; Histochemistry
• ISSN: 2278-4748; 2278-4802
• DOI: 10.14260/Jemds/2014/2677

Fibrous dysplasia is a benign skeletal developmental anomaly, which is manifested as a defect in osteoblastic differentiation and maturation of a normal bone that leads to structurally weak fibrous and osseous (bone-like) tissue. In normal bone formation, woven bone appears first and later matures into lamellar bone and in fibrous dysplasia, bone does not mature and development stops in the woven bone stage. Most commonly involved bones are femur, tibia, pelvis, ribs and skull. Small bones of hands or feet are rarely involved. This disorder is usually diagnosed in childhood or early adulthood and can affect one or several bones. Histopathology reveals abundant amount of fibrous tissue and disorganized bony trabeculae and spindle cells. Normal bone pattern is not demonstrated. Here we report a very rare case of fibrous dysplasia involving proximal phalanx of the hand diagnosed on radiological features with histopathological confirmation. KEYWORDS: Fibrous dysplasia, monostotic, polyostotic, x-ray, histopathology.