An Evidence-Based Approach to Orthobiologics for Tendon Disorders

Tendinopathy is a chronic injury that affects both the athletic and general population. Recalcitrant tendinopathy is both frustrating for patients and providers once typical conservative treatments have been exhausted. Current research in orthobiologics shows that they are safe and could improve pai...

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Bibliographic Details
Published inPhysical medicine and rehabilitation clinics of North America Vol. 34; no. 1; p. 83
Main Authors Abadin, Andre Armando, Orr, Jordan Pearl, Lloyd, Alexander Raphael, Henning, Phillip Troy, Pourcho, Adam
Format Journal Article
LanguageEnglish
Published United States 01.02.2023
Subjects
Humans
Pain
Platelet-Rich Plasma
Tendinopathy - therapy
Tendons
Tendinopathy
Mesenchymal signal cells
Tendinosis
Platelet-rich plasma (PRP
Orthobiologics
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Summary:Tendinopathy is a chronic injury that affects both the athletic and general population. Recalcitrant tendinopathy is both frustrating for patients and providers once typical conservative treatments have been exhausted. Current research in orthobiologics shows that they are safe and could improve pain and function in recalcitrant cases. Unfortunately, many studies show inconsistency in the content of the orthobiologic injectate and approach in treatment protocols. There are robust data to support the use of platelet-rich plasma for the treatment of recalcitrant common extensor tendinopathy and plantar fasciopathy, but high-quality random control trials are needed before drawing definitive conclusions for other tendinopathies.
ISSN:1558-1381
DOI:10.1016/j.pmr.2022.08.007