Clinical profile of COVID-19 infection in postvaccination individuals

• Published in: The American journal of managed care Vol. 28; no. 7; pp. e244 - e247
• Main Authors: Sashindran, V K, Kumar, K Rajesh, Nigam, Ankur, Mohakuda, Sourya Sourabh, Bhati, Navin, Mohapatra, Debasish
• Format: Journal Article
• Language: English
• Published: Jamesburg MultiMedia Healthcare Inc 01.07.2022
• Subjects: Chi-square test; Comorbidity; Coronaviruses; COVID-19 vaccines; Fever; Hospitalization; Infections; Medical research; Oxygen saturation; Pandemics; Population; Questionnaires; Severe acute respiratory syndrome coronavirus 2; India
• ISSN: 1088-0224; 1936-2692
• DOI: 10.37765/ajmc.2022.89182

There was a lower incidence of fever, cough, dyspnea, and requirement of hospitalization in the study population compared with the control group and previous epidemiological data. Am J Manag Care. 2022;28(7):e244-e247. https://doi.org/10.37765/ajmc.2022.89182 _____ Takeaway Points * This is the first study conducted among individuals who were detected to be COVID-19 positive after vaccination in India, the world's second most populous country, which accounts for about 16.6% of cases globally. * This study highlights the importance of vaccination as it shows favorable clinical outcomes in terms of fever, cough, shortness of breath, and lowest oxygen saturation recorded among vaccinated individuals. * There was also a significant reduction in the requirement of hospitalization among vaccinated individuals. * The study shows 50% higher chances of having mild disease after 2 doses of vaccination compared with after a single dose. _____ COVID-19, caused by SARS-CoV-2, was declared a pandemic on March 11, 2020, by the World Health Organization.1 The pandemic not only inflicted mortality and morbidity across the human race but also crippled the economies of affected nations. MATERIALS AND METHODS This descriptive observational study was conducted in individuals under the area of responsibility of a tertiary care center in northern India to study the clinical profile of patients with COVID-19 infection and various factors associated with severity of disease post COVID-19 vaccination. Statistical Analysis Descriptive statistics (frequency and percentages) were calculated for sample demographic characteristics and clinical features of the participants.