(Mes-Acr-Me)+ClO4– Catalyzed Visible Light-Supported, One-Pot Green Synthesis of 1,8-Naphthyridine-3-Carbonitriles

A novel, four-component one-pot green synthesis of biologically active 1,8-naphthyridines by a reaction of diverse aromatic aldehyde, malononitrile, 4-hydroxy substituted 1,6-dimethylpyridin-2(1 H )-one, corresponding aniline in EtOH catalyzed by 9-Mesityl-10-methylacridinium perchlorate [(Mes-Acr-M...

Full description

Saved in:
Bibliographic Details
Published inTopics in catalysis Vol. 68; no. 13; pp. 1440 - 1448
Main Authors Tabassum, Sumaiya, Govindaraju, Santhosh, Kendrekar, Pravin
Format Journal Article
LanguageEnglish
Published New York Springer US 01.07.2025
Springer Nature B.V
Subjects
Aldehydes
Aniline
Catalysis
Characterization and Evaluation of Materials
Chemical synthesis
Chemistry
Chemistry and Materials Science
Industrial Chemistry/Chemical Engineering
Malononitrile
Original Paper
Pharmacy
Physical Chemistry
Blue LED
9-Mesityl-10-methylacridinium perchlorate
Multicomponent reaction
1,8-Naphthyridines
Excellent yield
Online AccessGet full text

Cover

More Information
Summary:A novel, four-component one-pot green synthesis of biologically active 1,8-naphthyridines by a reaction of diverse aromatic aldehyde, malononitrile, 4-hydroxy substituted 1,6-dimethylpyridin-2(1 H )-one, corresponding aniline in EtOH catalyzed by 9-Mesityl-10-methylacridinium perchlorate [(Mes-Acr-Me) + ClO 4 – ] under visible light generated from a 24 W Blue LED wavelength 450–460 nm at 26 °C is reported. In contrast with the reported procedure, our methodology is diverse, versatile and has several favourable factors such as metal-free, excellent yields, shorter reaction durations, chromatography free and straightforward extraction process. Graphical Abstract
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ISSN:1022-5528
1572-9028
DOI:10.1007/s11244-022-01583-9