18F-FDG PET/CT demonstrating primary bone lymphoma of the extremities mimicking an inflammatory peripheral arthropathy

A 66-year-old woman presents with progressive bilateral swelling of her fingers, elbows, and toes. Initially thought to represent an inflammatory peripheral arthropathy, the patient underwent rheumatology review, but subsequent tissue biopsy confirmed diffuse large B-cell lymphoma. Results of bone m...

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Bibliographic Details
Published inClinical nuclear medicine Vol. 40; no. 2; p. 169
Main Authors Tachibana, Ayano, Robinson, Richard J, Patel, Chirag N
Format Journal Article
LanguageEnglish
Published United States 01.02.2015
Subjects
Aged
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - pathology
Diagnosis, Differential
Extremities - diagnostic imaging
Female
Fluorodeoxyglucose F18
Humans
Joint Diseases - diagnosis
Lymphoma, Large B-Cell, Diffuse - diagnostic imaging
Lymphoma, Large B-Cell, Diffuse - pathology
Multimodal Imaging
Positron-Emission Tomography
Radiopharmaceuticals
Tomography, X-Ray Computed
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Summary:A 66-year-old woman presents with progressive bilateral swelling of her fingers, elbows, and toes. Initially thought to represent an inflammatory peripheral arthropathy, the patient underwent rheumatology review, but subsequent tissue biopsy confirmed diffuse large B-cell lymphoma. Results of bone marrow biopsy and staging CT were negative. F-FDG PET/CT demonstrates FDG-avid bony and adjacent soft tissue disease limited to the extremities with an excellent metabolic response to primary chemotherapy. This is a rare case of primary bone lymphoma limited to the extremities mimicking an inflammatory peripheral arthropathy.
ISSN:1536-0229
DOI:10.1097/RLU.0000000000000550