EVALUATION OF INTRA-OPERATIVE HAEMODYNAMIC CHANGES AND DEGREE OF POST-OPERATIVE ANALGESIA USING PRE-INCISIONAL PERIPORTAL AND INTRA-PERITONEAL INJECTION OF LEVOBUPIVACAINE 0.25% IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY

• Published in: Journal of evolution of medical and dental sciences Vol. 5; no. 51; pp. 3272 - 3277
• Main Authors: Sharma, Sorabh, Goyal, Vipin Kumar, Chaturvedi, Shashikala, Gupta, Prakash
• Format: Journal Article
• Language: English
• Published: Akshantala Enterprises Private Limited 27.06.2016
• Subjects: Analgesia; Analysis; Cholecystectomy; Hemodynamics; Postoperative pain
• ISSN: 2278-4748; 2278-4802
• DOI: 10.14260/jemds/2016/759

Laparoscopic cholecystectomy is itself a lesser painful procedure. (1) but the various after-effects of pain such as difficulty in breathing and coughing, difficulty in moving around and various psychological and behavioural problems along with decreased secretion of Anti-Diuretic Hormone make good postoperative analgesia necessary. The various opioids, which are used for analgesia have various side effects like respiratory depression and also they increase the action of inflammatory mediators. AIMS AND OBJECTIVES The main aim of our study was, 1. To relieve the patients from postoperative pain and its adverse effects. 2. To decrease the amount of opioids administered and hence relieve from its side effects. (2) 3. To study the haemodynamic changes occurring intraoperatively. METHODOLOGY 50 patients were taken in L group and another 50 patients were taken in NS group. All patients were of ASA grade I and II; 0.25% inj. Levobupivacaine was administered to L group patients and only normal saline administered to patients of NS group. STATISTICAL ANALYSIS Data analysis was performed using SPSS 20 (IBM SPSS Statistics) for windows. VAS score was compared between two groups by repeated measure of analysis of variance. P value <0.05 was considered statistically significant. RESULT AND CONCLUSION Patients in L group showed better postoperative analgesia and better protection from nausea and vomiting. KEYWORDS Levobupivacaine, Laparoscopic Cholecystectomy, Postoperative Analgesia, Postoperative Nausea-Vomiting, Systolic Blood Pressure, Diastolic Blood Pressure, Pulse Rate, Spo2%, Vas Score.