Medical paleomicrobiology: problems and prospects

The study of microbial DNA from paleontological and archaeological samples is a powerful tool for estimating the molecular evolution of human pathogens. The paper is a retrospective review of the most significant achievements in medical paleomicrobiology. The subject of the discussion is the genetic...

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Bibliographic Details
Published inAntibiotiki i himioterapiâ Vol. 66; no. 5-6; pp. 72 - 77
Main Authors Goncharov, A. E., Kolodzhieva, V. V.
Format Journal Article
LanguageEnglish
Russian
Published LLC "Publishing House OKI" 30.08.2021
Subjects
ancient dna
evolution
microbiome
next generation sequencing
paleomicrobiology
pathogens
permafrost
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Summary:The study of microbial DNA from paleontological and archaeological samples is a powerful tool for estimating the molecular evolution of human pathogens. The paper is a retrospective review of the most significant achievements in medical paleomicrobiology. The subject of the discussion is the genetic diversity of ancient microbiomes including pathogenicity and antibiotic resistance genes. Paleomicrobiological studies of permafrost as a repository of pathogenic microbiota are highly promising.
ISSN:0235-2990
DOI:10.37489/0235-2990-2021-66-5-6-72-77