TBAF-catalyzed hydrosilylation for the reduction of aromatic nitriles

The selective catalytic hydrosilylation of functional groups is becoming an interesting tool for organic synthesis. In the present study, fluoride-catalyzed hydrosilylations of aromatic nitriles have been examined in detail. Using catalytic amounts of inexpensive tetra-n-butylammonium fluoride (TBAF...

Full description

Saved in:
Bibliographic Details
Published inNew journal of chemistry Vol. 37; no. 7; pp. 2061 - 2065
Main Authors Bornschein, Christoph, Werkmeister, Svenja, Junge, Kathrin, Beller, Matthias
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 01.01.2013
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
MECHANISTIC ASPECTS
KETONES
AMINATION
AMMONIA
HYDROSILANES
PRIMARY AMINES
SELECTIVE REDUCTION
ALDEHYDES
FLUORIDE
AMIDES
Online AccessGet full text

Cover

More Information
Summary:The selective catalytic hydrosilylation of functional groups is becoming an interesting tool for organic synthesis. In the present study, fluoride-catalyzed hydrosilylations of aromatic nitriles have been examined in detail. Using catalytic amounts of inexpensive tetra-n-butylammonium fluoride (TBAF) various aromatic nitriles are reduced in good yields under mild conditions.
ISSN:1144-0546
1369-9261
DOI:10.1039/c3nj00171g