In vitro and In vivo anti-inflammatory activity of leaves of Symplocos cochinchnensis (Lour) Moore ssp laurina

The anti-inflammatory activities of different extracts of leaves Symplocos cochinchnensis Lour ssp laurina (Symplococaceae) were investigated for In-vitro anti-inflammatory activity by human red blood cell membrane stabilization method. The methanol extract showed effective in-vitro anti-inflammator...

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Bibliographic Details
Published inBangladesh journal of pharmacology Vol. 3; no. 2; pp. 121 - 124
Main Authors Vadivu, Rajendran, Lakshmi, K.S.
Format Journal Article
LanguageEnglish
Published Bangladesh Pharmacological Society 01.12.2008
Subjects
Anti-inflammatory activity
Carrageenan
Symplocos cochinchnensis
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Summary:The anti-inflammatory activities of different extracts of leaves Symplocos cochinchnensis Lour ssp laurina (Symplococaceae) were investigated for In-vitro anti-inflammatory activity by human red blood cell membrane stabilization method. The methanol extract showed effective in-vitro anti-inflammatory activity was screened for in-vivo anti-inflammatory activity by carrageenan-induced paw edema in rat model. The potency of the extracts was compared with standard diclofenac (50 mg/kg). The methanol extract showed significant membrane stabilizing action on human red blood cell membrane and reduction of edema in carrageenan induced rat paw edema model.
ISSN:1991-007X
1991-0088
DOI:10.3329/bjp.v3i2.956