Characteristics of human saliva proteome and peptidome

Recent studies on the characteristics of saliva proteome and peptidome greatly expanded our understanding of this biological fluid. Athough many scientists consider saliva to be an ideal biosubstrate in diagnosis of the human body state; currently, the research in this area is at the data accumulati...

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Bibliographic Details
Published inHuman physiology Vol. 42; no. 4; pp. 463 - 468
Main Authors Kolesov, S. A., Fedulova, E. N., Lavrova, A. E.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.07.2016
Springer Nature B.V
Subjects
Biomedical and Life Sciences
Biomedicine
Glands
Human Physiology
Life Sciences
Microorganisms
Oral cavity
Proteomes
Reviews
Saliva
Standardization
Studies
saliva
diagnostics
proteomics
peptidomics
proteins
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Summary:Recent studies on the characteristics of saliva proteome and peptidome greatly expanded our understanding of this biological fluid. Athough many scientists consider saliva to be an ideal biosubstrate in diagnosis of the human body state; currently, the research in this area is at the data accumulation stage. The physiology of saliva and salivary glands, as well as characteristics of interaction between the saliva proteins and the oral cavity microorganisms, has been insufficiently studied yet. The lack of standardization in collecting the saliva samples and in the proteome research protocols, and the requirements for sample representativeness introduce discrepancies in the results obtained by different researchers. Addressing these problems will allow the wide use of saliva proteome as a complex indicator of the functional state of the human body.
ISSN:0362-1197
1608-3164
DOI:10.1134/S0362119716040058