Clinical study on electroacupuncture for perimenopause syndrome

• Published in: Journal of acupuncture and tuina science Vol. 9; no. 5; pp. 278 - 282
• Main Authors: Yi, Li, Yong, Xia, Shimin, Liu, Ziyong, Ju, Xiaolan, Shi, Miaogen, Chen, Ling, Cheng, Jinsen, He
• Format: Journal Article
• Language: English
• Published: Heidelberg Shanghai Research Institute of Acupuncture and Meridian 01.10.2011; Springer Nature B.V
• Subjects: Acupuncture; Electroacupuncture; Medicine; Medicine & Public Health; Special Topic Study; R246.3; Electroacupuncture; 雌二醇; Perimenopause Syndrome; 促卵泡生成素; Estradiol; 围绝经期综合征; 更年期综合征; Luteinizing Hormone; Climacteric Syndrome; Follicle-stimulating Hormone; 电针; 黄体生成素
• ISSN: 1672-3597; 1993-0399
• DOI: 10.1007/s11726-011-0531-3

Objective To observe the clinical effect of electroacupuncture in treating perimenopause syndrome (PMS) and explore its possible action mechanism. Methods All of 110 cases with PMS were randomized into group A [Guanyuan (CV 4) and Sanyinjiao (SP 6)] and group B [Neiguan (PC 6) and Zusanli (ST 36)], 55 cases in each. After 4-week treatments, the Kupperman Menopausal Index (KMI) was adopted to evaluate the therapeutic effect. Estradiol (E 2 ), follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were assayed respectively before and after treatments. Results The KMI decreased by 52.6% in group A, versus 47.4% in group B. The total effective rate was 93.6% in group A, versus 85.7% in group B, and the difference was not significant ( P >0.05). The content of E 2 both increased in the two groups after 4-week treatments ( P <0.05); the contents of FSH and LH dropped but without statistical difference ( P >0.05). Conclusion Both of the two acupoints groups can significantly lower KMI, and effectively increase the contents of E 2 in patients with PMS.