1H, 13C, and 15N resonance assignments and secondary structure prediction of the full-length transition state regulator AbrB from Bacillus anthracis

The AbrB protein is a transcription factor that regulates the expression of numerous essential genes during the cells transition phase state. AbrB from Bacillus anthracis is, nototriously, the principal protein responsible for anthrax toxin gene expression and is highly homologous to the much-studie...

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Bibliographic Details
Published inBiomolecular NMR assignments Vol. 6; no. 1; pp. 95 - 98
Main Authors Olson, Andrew L., Bobay, Benjamin G., Melander, Christian, Cavanagh, John
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Netherlands 01.04.2012
Subjects
Biochemistry
Biological and Medical Physics
Biophysics
Physics
Physics and Astronomy
Polymer Sciences
Transition state regulator
NMR
AbrB
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Summary:The AbrB protein is a transcription factor that regulates the expression of numerous essential genes during the cells transition phase state. AbrB from Bacillus anthracis is, nototriously, the principal protein responsible for anthrax toxin gene expression and is highly homologous to the much-studied AbrB protein from Bacillus subtilis having 85% sequence identity and the ability to regulate the same target promoters. Here we report backbone and sidechain resonance assignments and secondary structure prediction for the full-length AbrB protein from B. anthracis .
ISSN:1874-2718
1874-270X
DOI:10.1007/s12104-011-9333-2