The Effect of a Weak Static Magnetic Field in the Range of Magnitudes from a “Zero” Field (0.01 μT) to 100 μT on the Production of Reactive Oxygen Species in Nonactivated Neutrophils

• Published in: Biophysics (Oxford) Vol. 65; no. 3; pp. 443 - 447
• Main Authors: Novikov, V. V., Yablokova, E. V., Shaev, I. A., Fesenko, E. E.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.05.2020; Springer Nature B.V
• Subjects: Biological and Medical Physics; Biophysics; Cell Biophysics; Leukocytes (neutrophilic); Magnetic fields; Neutrophils; Oxidation; Peritoneum; Physics; Physics and Astronomy; Reactive oxygen species; hypomagnetic field; geomagnetic field; fluorescence; neutrophils; reactive oxygen species
• ISSN: 0006-3509; 1555-6654
• DOI: 10.1134/S0006350920030161

It was shown that 40-min exposure of peritoneal neutrophils to hypomagnetic conditions (with a residual field of 0.01 μT) caused a significant (25%) decrease in the intensity of intracellular dichlorofluorescein fluorescence. This effect of the weak magnetic field persisted if the constant magnetic field was increased to 1 μT. Upon further increase of the field to 2.5 μT, the effect of the field disappeared and reappeared at 5 μT in a reduced form, reaching a maximum at 7 μT. There was an equally pronounced and stable inhibitory effect under a sequential increase in the induction of a constant magnetic field (9, 15, and 19.5 μT), the degree of manifestation of which was significantly reduced only at 30 μT. Fluorescence intensity of the 2,7-dichlorodydrofluorescein oxidation products did not differ from the control values at a constant magnetic field of 45 μT. There was no observed effect on these processes under further increase of the field to 74 and 100 μT.